Martes 09 de Diciembre, 2008
 | Chelsea | vs. | CFR |  | 13:45 |
 | Roma | vs. | Bordeaux |  | 13:45 |
 | Panathinaikos | vs. | Anorthosis |  | 13:45 |
 | Werder Bremen | vs. | Inter de Milán |  | 13:45 |
 | Basilea | vs. | Sporting |  | 13:45 |
 | Barcelona | vs. | Shakhtar D. |  | 13:45 |
 | PSV | vs. | Liverpool |  | 13:45 |
 | Marsella | vs. | Atlético de Madrid |  | 13:45 |
Miércoles 10 de Diciembre, 2008
 | Manchester Utd. | vs. | AaB |  | 13:45 |
 | Celtic | vs. | Villarreal |  | 13:45 |
 | Steaua Bucurest | vs. | Fiorentina |  | 13:45 |
 | Lyon | vs. | Bayern Munich |  | 13:45 |
 | Porto | vs. | Arsenal |  | 13:45 |
 | Dynamo Kiev | vs. | Fenerbahçe SK |  | 13:45 |
 | Juventus | vs. | Bate |  | 13:45 |
 | Real Madrid | vs. | Zenit |  | 13:45 |
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